Certifications 2

SDS No.: 633048 V002.0
TEROSON MS 939 WH
Page 8 of 13
Serious eye damage/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
Trimethoxyvinylsilane
2768-02-7
not irritating
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Titanium dioxide
13463-67-7
not irritating
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
Trimethoxyvinylsilane
2768-02-7
not sensitising
Guinea pig maximisation
test
guinea pig
OECD Guideline 406 (Skin Sensitisation)
Titanium dioxide
13463-67-7
not sensitising
Mouse local lymphnode
assay (LLNA)
mouse
equivalent or similar to OECD Guideline
429 (Skin Sensitisation: Local Lymph
Node Assay)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Trimethoxyvinylsilane
2768-02-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Trimethoxyvinylsilane
2768-02-7
positive
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Trimethoxyvinylsilane
2768-02-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Titanium dioxide
13463-67-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Titanium dioxide
13463-67-7
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Titanium dioxide
13463-67-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Trimethoxyvinylsilane
2768-02-7
negative
intraperitoneal
mouse
other guideline:
Titanium dioxide
13463-67-7
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Carcinogenicity
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous components
CAS-No.
Result
Route of
application
Exposure
time /
Frequency
of treatment
Species
Sex
Method
Titanium dioxide
13463-67-7
not carcinogenic
inhalation
24 m
6 h/d; 5 d/w
rat
male/female
OECD Guideline 453
(Combined Chronic
Toxicity /
Carcinogenicity
Studies)