SDS

Material Name: OATEY PURPLE OR CLEAR PRIMER NSF LISTED
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Page 6 of 10
Issue Date 08/02/12 Revision 1.0000
Print Date: 9/27/2012
* * * Section 11 - Toxicological Information * * *
Acute Toxicity
Component Analysis - LD50/LC50
Acetone (67-64-1)
Oral LD50 Rat 5800 mg/kg
Methyl ethyl ketone (78-93-3)
Inhalation LC50 Mouse 32 g/m3 4 h; Oral LD50 Rat 2737 mg/kg; Dermal LD50 Rabbit 6480 mg/kg
Cyclohexanone (108-94-1)
Inhalation LC50 Rat 10.7 mg/L 4 h; Inhalation LC50 Rat 8000 ppm 4 h; Oral LD50 Rat 800 mg/kg; Dermal LD50
Rabbit 948 mg/kg
Tetrahydrofuran (109-99-9)
Inhalation LC50 Rat 53.9 mg/L 4 h; Inhalation LC50 Rat 180 mg/L 1 h; Oral LD50 Rat 1650 mg/kg
Potential Health Effects: Skin Corrosion Property/Stimulativeness
May cause irritation with redness, itching and pain. Methyl ethyl ketone and cyclohexanone may be absorbed
through the skin causing effects similar to those listed under inhalation.
Potential Health Effects: Eye Critical Damage/ Stimulativeness
Vapors may cause irritation. Direct contact may cause irritation with redness, stinging and tearing of the eyes.
May cause eye damage.
Potential Health Effects: Ingestion
Swallowing may cause abdominal pain, nausea, vomiting and diarrhea. Aspiration during swallowing or vomiting
can cause chemical pneumonia and lung damage. May cause kidney and liver damage.
Potential Health Effects: Inhalation
Vapors or mists may cause mucous membrane and respiratory irritation, coughing, headache, dizziness,
dullness, nausea, shortness of breath and vomiting. High concentrations may cause central nervous system
depression, narcosis and unconsciousness. May cause kidney, liver and lung damage.
Respiratory Organs Sensitization/Skin Sensitization
This product is not reported to have any skin sensitization effects.
Generative Cell Mutagenicity
Cyclohexanone has been positive in bacterial and mammalian assays. Acetone, methyl ethyl ketone and
tetrahydrofuran are generally thought not to be mutagenic.
Carcinogenicity
A: General Product Information
In 2012 USEPA Integrated Risk Information System (IRIS) reviewed a two species inhalation lifetime study on
THF conducted by NTP (1998). Male rats developed renal tumors and female mice developed liver tumors while
neither the female rats nor the male mice showed similar results. Because the carcinogenic mechanisms could
not be identified clearly in either species for either tumor, the EPA determined that the male rat and female mouse
findings are relevant to the assessment of carcinogenic potential in humans. Therefore, the IRIS review
concludes that these data in aggregate indicate that there is "suggestive evidence of carcinogenic potential"
following exposure to THF by all routes of exposure.