SDS

Material Name: OATEY PVC RAIN-R-SHINE BLUE CEMENT
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Page 7 of 11
Issue Date 09/07/12 Revision 2.0000
Print Date: 9/27/2012
Carcinogenicity
A: General Product Information
In 2012 USEPA Integrated Risk Information System (IRIS) reviewed a two species inhalation lifetime study on
THF conducted by NTP (1998). Male rats developed renal tumors and female mice developed liver tumors while
neither the female rats nor the male mice showed similar results. Because the carcinogenic mechanisms could
not be identified clearly in either species for either tumor, the EPA determined that the male rat and female mouse
findings are relevant to the assessment of carcinogenic potential in humans. Therefore, the IRIS review
concludes that these data in aggregate indicate that there is "suggestive evidence of carcinogenic potential"
following exposure to THF by all routes of exposure.
B: Component Carcinogenicity
Tetrahydrofuran (109-99-9)
ACGIH:
A3 - Confirmed Animal Carcinogen with Unknown Relevance to Humans
Cyclohexanone (108-94-1)
ACGIH:
A3 - Confirmed Animal Carcinogen with Unknown Relevance to Humans
IARC:
Monograph 71 [1999]; Monograph 47 [1989] (Group 3 (not classifiable))
Acetone (67-64-1)
ACGIH:
A4 - Not Classifiable as a Human Carcinogen
PVC (Chloroethylene, polymer) (9002-86-2)
ACGIH:
A4 - Not Classifiable as a Human Carcinogen
IARC:
Supplement 7 [1987]; Monograph 19 [1979] (Group 3 (not classifiable))
Silica, amorphous, fumed, crystalline-free (112945-52-5)
IARC:
Monograph 68 [1997] (listed under Amorphous silica) (Group 3 (not classifiable))
Reproductive Toxicity
Methyl ethyl ketone and cyclohexanone have been shown to cause embryofetal toxicity and birth defects in
laboratory animals. Acetone and tetrahydrofuran has been found to cause adverse developmental effects only
when exposure levels cause other toxic effects to the mother.
Specified Target Organ General Toxicity: Single Exposure
May cause respiratory irritation. Inhalation of high concentrations may cause central nervous system depression,
narcosis and unconsciousness. May cause kidney, liver and lung damage.
Specified Target Organ General Toxicity: Repeated Exposure
This product is not reported to have any specific target organ toxicity repeat exposure effects.
Aspiration Respiratory Organs Hazard
Aspiration during swallowing or vomiting can cause chemical pneumonia and lung damage. May cause kidney
and liver damage.
* * * Section 12 - Ecological Information * * *
Ecotoxicity
A: General Product Information
This product is not expected to be toxic to aquatic organisms.
B: Component Analysis - Ecotoxicity - Aquatic Toxicity
Tetrahydrofuran (109-99-9)
Test & Species
Conditions